Anti-PD-1-induced high-grade hepatitis associated with corticosteroid-resistant T cells: a case report
- Creator: McGuire, Helen M. , Shklovskaya, Elena , Edwards, Jarem , Trevillian, Paul R. , McCaughan, Geoffrey W. , Bertolino, Patrick , McKenzie, Catriona , Gourlay, Ralph , Gallagher, Stuart J. , Fazekas de St. Groth, Barbara , Hersey, Peter
- Resource Type: journal article
- Date: 2018
Immunotherapy-induced sarcoidosis in patients with melanoma treated with PD-1 checkpoint inhibitors: Case series and immunophenotypic analysis
- Creator: Lomax, Anna J. , McGuire, Helen M. , Gupta, Sandeep K. , Hollingsworth, Jane , Kim, Haewon , Fazekas de St Groth, Barbara , McGill, Neil , McNeil, Catriona , Choi, Clara J. , Hersey, Peter , Karikios, Deme , Shannon, Kerwin , van Hal, Sebastian , Carr, Urszula , Crotty, Anne
- Resource Type: journal article
- Date: 2017
Association of pembrolizumab with tumor response and survival among patients with advanced melanoma
- Creator: Ribas, Antoni , Hamid, Omid , Gangadhar, Tara C. , Hersey, Peter , Dronca, Roxana , Joseph, Richard W. , Zarour, Hassane , Chmielowski, Bartosz , Lawrence, Donald P. , Algazi, Alain , Rizvi, Naiyer A. , Hoffner, Brianna , Daud, Adil , Mateus, Christine , Gergich, Kevin , Lindia, Jill A. , Giannotti, Maxine , Li, Xiaoyun Nicole , Ebbinghaus, Scott , Kang, S. Peter , Robert, Caroline , Hodi, F. Stephen , Wolchok, Jedd D. , Kefford, Richard , Joshua, Anthony M. , Patnaik, Amita , Hwu, Wen-Jen , Weber, Jeffrey S.
- Resource Type: journal article
- Date: 2016
Evaluation of immune-related response criteria and RECIST v1.1 in patients with advanced melanoma treated with pembrolizumab
- Creator: Hodi, F. Stephen , Hwu, Wen-Jen , Joshua, Anthony M. , Hersey, Peter , Dronca, Roxana , Joseph, Richard , Hille, Darcy , Xue, Dahai , Li, Xiaoyun Nicole , Kang, S. Peter , Ebbinghaus, Scot , Perrone, Andrea , Kefford, Richard , Wolchok, Jedd D. , Weber, Jeffrey S. , Daud, Adil , Hamid, Omid , Patnaik, Amita , Ribas, Antoni , Robert, Caroline , Gangadhar, Tara C.
- Resource Type: journal article
- Date: 2016
EZH2 as a mediator of treatment resistance in melanoma
- Creator: Tiffen, Jessamy C. , Gallagher, Stuart J. , Tseng, Hsin-Yi , Filipp, Fabian V. , Fazekas de St Groth, Barbara , Hersey, Peter
- Resource Type: journal article
- Date: 2016
Programmed death-ligand 1 expression and response to the anti-programmed death 1 antibody pembrolizumab in melanoma
- Creator: Daud, Adil I , Wolchok, Jedd D. , Joseph, Richard , Gangadhar, Tara C. , Dronca, Roxana , Patnaik, Amita , Zarour, Hassane , Roach, Charlotte , Toland, Grant , Lunceford, Jared K. , Li, Xiaoyun Nicole , Emancipator, Kenneth , Robert, Caroline , Dolled-Filhart, Marisa , Kang, S. Peter , Ebbinghaus, Scot , Hamid, Omid , Hwu, Wen-Jen , Weber, Jeffrey S. , Ribas, Antoni , Hodi, F. Stephen , Joshua, Anthony M. , Kefford, Richard , Hersey, Peter
- Resource Type: journal article
- Date: 2016
Somatic copy number amplification and hyperactivating somatic mutations of EZH2 correlate with DNA methylation and drive epigenetic silencing of genes involved in tumor suppression and immune responses in melanoma
- Creator: Tiffen, Jessamy , Wilson, Stephen , Gallagher, Stuart J. , Hersey, Peter , Filipp, Fabian V.
- Resource Type: journal article
- Date: 2016
Melanoma early detection and awareness: how countries developing melanoma awareness programs could benefit from melanoma-proficient countries
- Creator: Wainstein, Alberto , Algarra, Salvador Martin , Whitaker, Dagmar , Quirt, Ian , Hauschild, Axel , Rutkowski, Piotr , Bastholt, Lars , Cinat, Gabriela , Demidov, Lev , Grob, Jean Jacques , Guo, Jun , Hersey, Peter , Espinosa, Enrique , Schachter, Jacob
- Resource Type: journal article
- Date: 2015
Side effects and toxicities of targeted therapies in stage IV melanoma
- Creator: Ascierto, Paolo A. , Bastholt, Lars , Hersey, Peter , Cinat, Gabriela , Eggermont, Alexander M. M. , Hauschild, Axel , Espinosa, Enrique , Robert, Caroline
- Resource Type: journal article
- Date: 2015
Macrophage migration inhibitory factor engages PI3K/Akt signalling and is a prognostic factor in metastatic melanoma
- Creator: Oliveira, Camila S. , de Bock, Charles E. , Molloy, Timothy J. , Sadeqzadeh, Elham , Geng, Xin Yan , Hersey, Peter , Zhang, Xu Dong , Thorne, Rick F.
- Resource Type: journal article
- Date: 2014
Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress
- Creator: Croft, Amanda , Tay, Kwang H. , Zhang, Xu D. , Boyd, Suzanah C. , Guo, Su T. , Jiang, Chen C. , Lai, Fritz , Tseng, Hsin-Yi , Jin, Lei , Rizos, Helen , Hersey, Peter
- Resource Type: journal article
- Date: 2014
OBATOCLAX and ABT-737 induce ER stress responses in human melanoma cells that limit induction of apoptosis
- Creator: Wroblewski, David , Jiang, Chen Chen , Croft, Amanda , Farrelly, Margaret L. , Zhang, Xu Dong , Hersey, Peter
- Resource Type: journal article
- Date: 2013
Pharmacodynamic effects and mechanisms of resistance to Vemurafenib in patients with metastatic melanoma
- Creator: Trunzer, Kerstin , Pavlick, Anna C. , Hersey, Peter , Long, Georgina V. , Lawrence, Donald , Ott, Patrick A. , Amaravadi, Ravi K. , Lewis, Karl D. , Puzanov, Igor , Lo, Roger S. , Koehler, Astrid , Kockx, Mark , Schuchter, Lynn , Spleiss, Olivia , Schell-Steven, Annette , Gilbert, Houston N. , Cockey, Louise , Bollag, Gideon , Lee, Richard J. , Joe, Andrew K. , Sosman, Jeffrey A. , Ribas, Antoni , Gonzalez, Rene , McArthur, Grant A. , Hutson, Thomas E. , Moschos, Stergios J. , Flaherty, Keith T. , Kim, Kevin B. , Weber, Jeffrey S.
- Resource Type: journal article
- Date: 2013
PI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanoma
- Creator: Ye, Yan , Jin, Lei , Tay, Kwang Hong , Tseng, Hsin-Yi , Guo, Su Tang , de Bock, Charles E. , Jiang, Chen Chen , Wang, Chun Yang , Wu, Mian , Zhang, Lie Jie , Hersey, Peter , Scolyer, Richard A. , Wilmott, James S. , Zhang, Xu Dong , Hu, Wang Lai , Yosufi, Benafsha , Thorne, Rick F. , Liu, Tao , Rizos, Helen , Yan, Xu Guang , Dong, Li
- Resource Type: journal article
- Date: 2013
Regulators of global genome repair do not respond to DNA damaging therapy but correlate with survival in melanoma
- Creator: Bowden, Nikola A. , Ashton, Katie A. , Scott, Rodney J. , Vilain, Ricardo E. , Avery-Kiejda, Kelly A. , Davey, Ryan J. , Murray, Heather C. , Budden, Timothy , Braye, Stephen G. , Zhang, Xu Dong , Hersey, Peter
- Resource Type: journal article
- Date: 2013
Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
- Creator: Hamid, Omid , Robert, Caroline , Dronca, Roxana , Gangadhar, Tara C. , Patnaik, Amita , Zarour, Hassane , Joshua, Anthony M. , Gergich, Kevin , Elassaiss-Schaap, Jeroen , Algazi, Alain , Mateus, Christine , Boasberg, Peter , Daud, Adil , Tumeh, Paul C. , Chmielowski, Bartosz , Ebbinghaus, Scot W. , Li, Xiaoyun Nicole , Kang, S. Peter , Ribas, Antoni , Hodi, F. Stephen , Hwu, Wen-Jen , Kefford, Richard , Wolchok, Jedd D. , Hersey, Peter , Joseph, Richard W. , Weber, Jeffrey S.
- Resource Type: journal article
- Date: 2013
The BH3-mimetic ABT-737 sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors but does not reverse acquired resistance
- Creator: Wroblewski, David , Mijatov, Branka , Mohana-Kumaran, Nethia , Lai, Fritz , Gallagher, Stuart J. , Haass, Nikolas K. , Zhang, Xu Dong , Hersey, Peter
- Resource Type: journal article
- Date: 2013
Evidence for upregulation of Bim and the splicing factor SRp55 in melanoma cells from patients treated with selective BRAF inhibitors
- Creator: Lai, Fritz , Jiang, Chen Chen , Farrelly, Margaret L. , Zhang, Xu Dong , Hersey, Peter
- Resource Type: journal article
- Date: 2012
Histone deacetylases (HDACs) as mediators of resistance to apoptosis in melanoma and as targets for combination therapy with selective BRAF inhibitors
- Creator: Lai, Fritz , Jin, Lei , Gallagher, Stuart , Mijatov, Branka , Zhang, Xu Dong , Hersey, Peter
- Resource Type: book chapter
- Date: 2012
Modulation of NOXA and MCL-1 as a strategy for sensitizing melanoma cells to the BH3-mimetic ABT-737
- Creator: Lucas, Keryn M. , Mohana-Kumaran, Nethia , Lau, Diana , Zhang, Xu Dong , Hersey, Peter , Huang, David C. , Weninger, Wolfgang , Haass, Nikolas K. , Allen, John D.
- Resource Type: journal article
- Date: 2012